BackgroundIn the Canadian Alliance for Healthy Hearts and Minds (CAHHM) cohort, participants underwent magnetic resonance imaging (MRI) of the brain, heart, and abdomen, that generated incidental findings (IFs). The approach to managing these unexpected results remain a complex issue. Our objectives were to describe the CAHHM policy for the management of IFs, to understand the impact of disclosing IFs to healthy research participants, and to reflect on the ethical obligations of researchers in future MRI studies.MethodsBetween 2013 and 2019, 8252 participants (...) (mean age 58 ± 9 years, 54% women) were recruited with a follow-up questionnaire administered to 909 participants (40% response rate) at 1-year. The CAHHM policy followed a restricted approach, whereby routine feedback on IFs was not provided. Only IFs of severe structural abnormalities were reported.ResultsSevere structural abnormalities occurred in 8.3% (95% confidence interval 7.7–8.9%) of participants, with the highest proportions found in the brain (4.2%) and abdomen (3.1%). The majority of participants (97%) informed of an IF reported no change in quality of life, with 3% of participants reporting that the knowledge of an IF negatively impacted their quality of life. Furthermore, 50% reported increased stress in learning about an IF, and in 95%, the discovery of an IF did not adversely impact his/her life insurance policy. Most participants (90%) would enrol in the study again and perceived the MRI scan to be beneficial, regardless of whether they were informed of IFs. While the implications of a restricted approach to IF management was perceived to be mostly positive, a degree of diagnostic misconception was present amongst participants, indicating the importance of a more thorough consent process to support participant autonomy.ConclusionThe management of IFs from research MRI scans remain a challenging issue, as participants may experience stress and a reduced quality of life when IFs are disclosed. The restricted approach to IF management in CAHHM demonstrated a fair fulfillment of the overarching ethical principles of respect for autonomy, concern for wellbeing, and justice. The approach outlined in the CAHHM policy may serve as a framework for future research studies.Clinical trial registrationhttps://clinicaltrials.gov/ct2/show/nct02220582. (shrink)

I. General introduction to philosophy, by Cardinal Mercier. Cosmology, by D. Nys. Psychology, by Cardinal Mercier. Criteriology, by Cardinal Mercier. General metaphysics; or, Ontology, by Cardinal Mercier. Appendix to Cosmology, by D. Nys.--II. Natural theology; or, Theodicy, by Cardinal Mercier. Logic, by Cardinal Mercier. Ethics: General ethics, by A. Arendt (based on Cardinal Mercier's notes); Special ethics, by J. Halleux. History of philosophy, by M. de Wulf. Synopsis in the form of the principal theses. Glossary of scholastic terms, by G. (...) Simons. (shrink)

Socrates is one of the most important yet enigmatic philosophers of all time; his fame has endured for centuries despite the fact that he never actually wrote anything. In 399 B.C.E., he was tried on the charge of impiety by the citizens of Athens, convicted by a jury, and sentenced to death (ordered to drink poison derived from hemlock). About these facts there is no disagreement. However, as the sources collected in this book and the scholarly essays that follow them (...) show, several of even the most basic facts about these events were controversial in antiquity, and the questions persist today: How and why was Socrates brought to trial? Why did the jurors, members of the world's first democracy, find him guilty? When he was given an opportunity to escape execution, why did he refuse to do so and instead accept the punishment that he and his friends agreed was unjustly assigned to him? How exactly did Socrates die? Differences of opinion on these and other issues continue to arouse our curiosity and to challenge new generations of students and scholars. The Trial and Execution of Socrates: Sources and Controversies is the first work to collect in one place all of the major ancient sources on Socrates' death--those of both his critics and his defenders--as well as recent scholarly views. Part I includes new translations of Plato's Euthyphro, Apology, Crito, and the death scene from Phaedo, as well as other ancient sources that shed light on Socrates' trial and execution. Part II features some of the most influential recent scholarship on this historically momentous event with work by M. F. Burnyeat, Robert Parker, Mark L. McPherran, Thomas C. Brickhouse and Nicholas D. Smith, Richard Kraut, Christopher Gill, and Enid Bloch (whose essay is published here for the first time). Ideal for undergraduate surveys of ancient Greek philosophy and upper-level courses on Socrates and Socratic philosophy, this unique collection provides an unprecedented look into the many perplexing questions surrounding the trial and execution of this remarkable man. (shrink)

This volume brings together mostly previously unpublished studies by prominent historians, classicists, and philosophers on the roles and effects of religion in Socratic philosophy and on the trial of Socrates. Among the contributors are Thomas C. Brickhouse, Asli Gocer, Richard Kraut, Mark L. McPherran, Robert C. T. Parker, C. D. C. Reeve, Nicholas D. Smith, Gregory Vlastos, Stephen A. White, and Paul B. Woodruff.

pt. I. Ethics, by J. H. Tufts. Aesthetics, by D. H. Parker. Axiology, by W. M. Urban. Philosophy of law, by Roscoe Pound. Philosophy of history, by J. E. Boodin. Philosophy of science, by V. F. Lenzen. Philosophy of life, by A. N. Whitehead. Metaphysics, by E. W. Hall. Theology and metaphysics, by D. C. Mackintosh.--pt. II. Philosophy of the twentieth century, by Bertrand Russell. Kantianism, by A. C. Ewing. Philosophy of Hegelianism, by Richard Hoenigswald. The humanism of St. (...) Thomas Aquinas, by Jacques Maritain. Transcendental absolutism, by George Santayana. (shrink)

The term “euthanasia” is used in conflicting ways in the bioethical literature, as is the term “assisted suicide,” resulting in definitional confusion, ambiguities, and biases which are counterproductive to ethical and legal discourse. I aim to rectify this problem in two parts. Firstly, I explore a range of conflicting definitions and identify six disputed definitional factors, based on distinctions between (1) killing versus letting die, (2) fully intended versus partially intended versus merely foreseen deaths, (3) voluntary versus nonvoluntary versus involuntary (...) decisions, (4) terminally ill versus non-terminally ill patients, (5) patients who are fully conscious versus those in permanent comas or persistent vegetative states, and (6) patients who are suffering versus those who are not. Secondly, I distil these factors into six “building blocks” and combine them to develop an unambiguous, value-neutral taxonomy of “end-of-life practices.” I hope that this taxonomy provides much-needed clarification and a solid foundation for future ethical and legal discourse. (shrink)

Volume 20, Issue 7, July 2020, Page 139-141.

The commonly held view that Wittgensteinian philosophy of religion entails an irrationalist defense of religion known as 'fideism' loses plausibility when contrasted with recent scholarship on Wittgenstein's corpus, biography, and other sources. This book reevaluates the place of Wittgenstein in the philosophy of religion and charts a path forward for the subfield by advancing three themes. The first is that philosophers of religion should question received interpretations of philosophers, such as Wittgenstein, as well as the meanings of key terms used (...) in interpretations, such as 'fideism'. The second theme is that Wittgenstein's philosophy, across his corpus, pursues a particular end: a searching clarity or perspicuity. The third theme is that with the rise of various religious movements within societies and around the world in recent decades, philosophy of religion has important tasks in clarifying global conversations on living well amidst human diversities and contemplating philosophy as a vocation. (shrink)

Detection theory has been applied to a host of varied problems (for example, measuring the accuracy of diagnostic systems or reliability of lie detection tests) and extends far beyond the detection of signals. This book is a primer on the subject.

In a fair, infinite lottery, it is possible to conclude that drawing a number divisible by four is strictly less likely than drawing an even number; and, with apparently equal cogency, that drawing a number divisible by four is equally as likely as drawing an even number.

A typical thesis of contemporary materialism holds that mental properties and events supervene on, without being reducible to, physical properties and events. Many philosophers have grown skeptical about the causal efficacy of irreducibly supervenient properties, however, and one of the main reasons is an assumption about causation which Jaegwon Kim calls the causal exclusion principle. I argue here that this principle runs afoul of cases of genuine causal overdetermination.Many would argue that causal overdetermination is impossible anyway, but a careful analysis (...) of these arguments shows them to be misguided. Finally, I examine the reasons given in support of the causal exclusion principle, and I conclude that it is plausible if, and probably only if, a certain view of the nature of causation turns out to be correct. Since that view of causation is unacceptable to nonreductivists on other grounds, however, it turns out that exclusion-based arguments essentially beg the question. (shrink)

Do we owe it to future generations, as a requirement of justice, to take action to mitigate anthropogenic climate change? This paper examines the implications of Derek Parfit’s notorious non-identity problem for that question. An argument from Jörg Tremmel that the non-identity effect of climate policy is “insignificant” is examined and found wanting, and a contrastive, difference-making approach for comparing different choices’ non-identity effects is developed. Using the approach, it is argued that the non-identity effect of a given policy response (...) to climate change depends on the contrasting policy. Compared to a baseline scenario without further mitigation, the non-identity effect of choosing to limit climate change to 1.5°C would be highly significant. (shrink)

My essay ‘Weakening the ethical distinction between euthanasia, palliative opioid use and palliative sedation’ has recently generated some critique which I will attempt to address in this response. Regarding the empirical question of whether palliative opioid and sedative use shorten survival time, Schofieldet alraise the three concerns that my literature review contains a cherry-picking bias through focusing solely on the palliative care population, that continuous deep palliative sedation falls beyond the scope of routine palliative care, and that my research may (...) contribute to opiophobia and be harmful to palliative care provision globally. Materstvedt argues that euthanasia ‘ends’ rather than ‘relieves’ suffering and is not a treatment, and that the arguments in my essay are therefore predicated on a ‘category mistake’ and are a non-starter. Symons and Giebel both raise the concern that my Kantian and Millian interpretation of the Doctrine of Double Effect is anachronistic, and that when interpreted from the contemporaneous perspective of Aquinas it is a sound ethical principle. Giebel also argues that palliative opioid and sedative use do meet the Doctrine of Double Effect’s four criteria on this Thomistic account, and that it does not contradict the Doctrine of the Sanctity of Human Life. In this response I will explore and defend against most of these claims, in doing so clarifying my original argument that the empirical and ethical differences between palliative opioid/sedative use and euthanasia may not be as significant as often believed, thereby advancing the case for euthanasia. (shrink)

Can an act harm someone—a future someone, someone who does not exist yet but will—if that person would never exist but for that very action? This is one question raised by the non-identity problem. Many would argue that the answer is No: an action harms someone only insofar as it is worse for her, and an action cannot be worse for someone if she would not exist without it. The first part of this paper contends that the plausibility of the (...) ‘no harm’ argument stems from an equivocation. The second half argues for an account of harm that is both causal and contrastive. Finally, the paper contends that the contrastive account disarms the no harm argument and furthermore neutralizes a related argument that has been problematic for some previously proposed solutions to the non-identity problem. (shrink)

In this clear and up-to-date introduction, Thomas D. Senor lays the philosophical foundation needed to understand the justification of memory belief. This book explores traditional accounts of the justification of memory belief and examines the resources that prominent positions in contemporary epistemology have to offer theories of the memorial justification. Along the way, epistemic conservatism, evidentialism, foundationalism, phenomenal conservatism, reliabilism, and preservationism all feature. Study Questions and annotated Further Reading guides at the end of each chapter make this book (...) ideal for classroom use and independent study. Written in very clear prose, A Critical Introduction to the Epistemology of Memory is a valuable resource for students approaching epistemology for the first time or those looking to advance their understanding of a core area of philosophy. (shrink)

D. O. Thomas; XIII—Obedience to Conscience, Proceedings of the Aristotelian Society, Volume 64, Issue 1, 1 June 1964, Pages 243–258, https://doi.org/10.1093/ari.

That 'what all the gods love is holy (pious) and, on the other hand, what they all hate is unholy (impious)' is not an adequate account of the holy. The key to understanding the argument is found to rest in the epagogai and in the principle of substitutibility employed later in socrates' argument. I contend that not only is socrates' argument valid, but it is capable of application to a large class of accounts both theological and sociological.

This book is the first study to focus on the reception of Paul's link between resurrection and salvation, revealing its profound effect on early Christian theology - not only eschatology, but also anthropology, pneumatology, ethics, and soteriology. Thomas D. McGlothlin traces the roots of the strong tension on the matter in ancient Judaism and then offers deep readings of the topic by key theologians of pre-Nicene Christianity, who argued on both sides of the issue of the fleshliness of the (...) resurrected body. McGlothlin unravels the surprising continuities that emerge between Irenaeus, Origen, and the Valentinians, as well as deep disagreements between allies like Irenaeus and Tertullian. (shrink)

The American Journal of Bioethics, Volume 11, Issue 9, Page 12-13, September 2011.

Condorcet's jury theorem shows that when the members of a group have noisy but independent information about what is best for the group as a whole, majority decisions tend to outperform dictatorial ones. When voting is supplemented by communication, however, the resulting interdependencies between decision makers can strengthen or undermine this effect: they can facilitate information pooling, but also amplify errors. We consider an intriguing non-human case of independent information pooling combined with communication: the case of nest-site choice by honeybee (...) (Apis mellifera) swarms. It is empirically well documented that when there are different nest sites that vary in quality, the bees usually choose the best one. We develop a new agent-based model of the bees' decision process and show that its remarkable reliability stems from a particular interplay of independence and interdependence between the bees. (shrink)

Father Williams explains how the conscience is formed through our training and experiences and informed by the Holy Spirit, making it an essential tool for daily living. He uses familiar and surprising characters to illustrate the positive choices conscience can direct--and the disaster that results when a conscience is undeveloped or ignored. Questions he tackles include "Is it more important to be smart or good?""Is there a morally right thing to do in every situation?" and "Is the Christian moral life (...) an exciting adventure, or a necessary burden?" Rich, provocative, and practical for everyday decision making, KNOWING RIGHT FROM WRONG is a must-read for all who hunger for personal holiness. (shrink)

D.O. Thomas; VI*—The Duty to Trust, Proceedings of the Aristotelian Society, Volume 79, Issue 1, 1 June 1979, Pages 89–102, https://doi.org/10.1093/aristotelian.

In this paper, I offer a defense of what I dub “religious rationality pluralism”—that is, that people of various religions can be rational in holding a variety of religious perspectives. I distinguish two arguments against this position: the Uniqueness argument and the Disagreement argument. The aims of this essay are to argue that the Uniqueness thesis is ambiguous between two readings, that while one version of the thesis is quite plausible, it cannot be successfully used to argue against rationality pluralism, (...) and the version of the thesis that would support the argument is false. (shrink)

Stories of Philosophy is an introduction to philosophy textbook that combines both fiction and philosophical discussion. It combines compelling stories devoted to particular philosophical problems followed by clear and detailed guided discussions of the topics and ideas explored within the fictional stories. The text includes chapters on Logic, Appearance and Reality, The Nature of Mind, Freedom and Responsibility, The Existence of God, and Morality. Each chapter has several highly praised pedagogical features, including chapter-opening learning objectives, boldfaced key terms, questions for (...) discussion, definitions of terms, and suggested further readings. It will be accompanied by online support material for the instructor and the student. (shrink)

People are typically grateful for medical technologies used in the treatment of illness or injury. This chapter explores how Lucas has led Star Wars audiences astray into accepting false beliefs and fallacies about the value of technology, particularly in a medical context. Via the naturalistic fallacy, Lucas conveys the false belief that most technology is “unnatural” and so is bad, harmful, or associated with the dark side. Lucas is not wrong that technology can be fearful, but its value depends in (...) part on how it's intended to be used. Even the use of some medical technologies that can extend life raise questions about whether they should be used in all cases. Many bioethical conflicts center around whether a seriously ill or injured person would want certain medical interventions used to extend their life, given potential trade‐offs. Lucas's portrayal of technology in Star Wars is biased against its true value in societies. (shrink)

A primary fiduciary bond, rarely examined, is that of neighbor. I distinguish this bond from others that may overlap it, those of fellow citizen or compatriot. I argue that the nature of moral identity and the nature of moral formation require moral agents to acknowledge the fiduciary duties of neighbor.